Transsexuals in the Hindu Scriptures

238.           VISHNUPURANAM

Mitra and Varuna; but the ceremony being unsuccessful on aceount of some irregularity from the presiding priest: daughter Ila was born. But by the mercy of the two deities however, her sex was changed and she became a man under the name of Sudyumna. And he again became a woman under an imprecation (from Siva) near the hermitage of Buddha, the son of the moon.

One day while she was walking near the hermitage of Buddha, he became attached to her and beget on her a son named Pururavas. After his birth, the noble Rishis, desiring to restore Sudyumna to his sex, prayed to the glorious Vishnu who is the essence of the four Vedas, of mind, of every thing and of nothing and who is the sacrificed male. By his mercy us: once more became Sudyumna, in which character he had three sons, Utkala, Gaya and Vinata.

On account of his having been formerly born a female he did not receive any portion of his paternal kingdom. His father however at the request of Vasistha conferred upon him the city of Pratishta, and he gave it to Pururavas.

Of the other sons of Mann, Prishadhra, on account of the
sin consequent upon slaying a cow, was degraded to the conditions of a Sudra.

The above instance of the Divine turning someone transsexual is not even the most notable case of transsexualism in the Hindu traditions.  Certainly the most notable case of a transformation of someone from one biological gender to another is that of Vishnu/Krishna becoming Devi Mohini.

Shiva hooks up with and somehow impregnates Vishnu in His form as a Her, Mohini, and She gives birth to Ayyappa, the Protector of Created Beings, who I believe later reincarnated as Jeshua ben Joseph, aka Jesus Christ.

Ayyappa and His Brothers 

Ganesha and Kartikeya

Shiva and Mohini-Vishnu with Their infant Son Ayyappa/Shasta

For more on that theory regarding the drama and dharma of the Divine, see this post:  http://karma-dharma-bhutadaya.blogspot.com/2017/05/the-true-identity-of-jesus-revealed.html